Choose the Iso Pocket 3.0 if you want a structured 600ml bottle with an expanding zipped pocket for nutrition, keys or other small essentials. The Iso Versa 2.0 uses the same capacity and structured bottle approach but positions the load differently, with multiple hand positions and the option to move it farther towards the wrist or arm.
The 550 Pocket combines a more flexible 550ml hybrid bottle with expandable zipped storage. The 550 Race 2.0 uses the same hybrid bottle approach in a more minimalist design without a storage pocket.
Start by deciding whether you prefer a structured or more flexible bottle, then whether you need storage and which retention system best suits how you want the bottle to sit on your hand.